Literature summary extracted from

Ganter, M.T.; Roux, J.; Su, G.; Lynch, S.V.; Deutschman, C.S.; Weiss, Y.G.; Christiaans, S.C.; Myazawa, B.; Kipnis, E.; Wiener-Kronish, J.P.; Howard, M.; Pittet, J.F.
Role of small GTPases and alphavbeta5 integrin in Pseudomonas aeruginosa-induced increase in lung endothelial permeability (2009), Am. J. Respir. Cell Mol. Biol., 40, 108-118.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
3.6.5.2	additional information	exposure of confluent lung endothelial cell monolayers to wild type Pseudomonase aeruginosa strain PAK causes a significant increase in RhoA activity within 10 min	Bos taurus

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.6.5.2	additional information	exposure of confluent lung endothelial cell monolayers to wild type Pseudomonase aeruginosa strain PAK causes a significant decrease in Rac1 activity within 10 min	Bos taurus

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.6.5.2	Bos taurus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.6.5.2	lung endothelium	-	Bos taurus	-
3.6.5.2	pulmonary artery endothelial cell	macrovascular lung pulmonary artery endothelial cell	Bos taurus	-

Synonyms

EC Number	Synonyms	Comment	Organism
3.6.5.2	Rac1	-	Bos taurus
3.6.5.2	RhoA	-	Bos taurus

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Release 2023.1 (January 2023)